Volume 6, Number 2 (Occupational Medicine 2014)                   tkj 2014, 6(2): 32-43 | Back to browse issues page

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Choobineh S, Akbarzadeh H, Naghizadeh H. Effect of vitamin E supplementation on lipid peroxidation and the antioxidant defense responses following an exhausting aerobic exercise. tkj. 2014; 6 (2) :32-43
URL: http://tkj.ssu.ac.ir/article-1-309-en.html

1. Department of Physical Education & Sport Sciences Department of Physical Education & Sport Sciences, University of Ardakan , Naghizadeh2011@gmail.com
Abstract:   (2058 Views)
Background: physical exercise could induce lipid peroxidation as a result of oxidative stress. And intake of antioxidant compound may alleviate this stress by enhancing antioxidant defense. This study aimed to investigate the effect of vitamin E supplementation as an antioxidant on the lipid peroxidation and serum total antioxidant capacity following exhaustive continuous aerobic exercise in wistar rats. Methods: 28 wistar rats aged 4 month were assigned randomly into one of 4 groups: rest, rest vitamin E, continuous aerobic exercise, and continuous aerobic exercise-vitamin E. The supplement groups, were administrated a dose of 250 IU per one kilogram of daily intake food for one month of supplementation. All groups were subjected a familiarization treadmill protocol for two weeks. Finally, rats in continuous aerobic exercise groups exercised at 70% vo2 max. The running speed was 20 m/min at a gradient 5%. Serum malon dealdehyde (MDA) and total antioxidant capacity (TAC) were measured. Data were analyzed by one way ANOVA and sheffe post hoc at P<0.05 level. Results: The MDA increased significantly following continuous aerobic exercise (P<0.05) but vitamin E could not decrease significantly the elevated response of MDA following exercise. However The TAC was higher significantly in continuous aerobic vitamin E group compare to the rest group (P<0.01). Conclusion: vitamin E supplementation despite of enhancement of the antioxidant capacity cannot prevent lipid peroxidation following continuous aerobic exercise in wistar rats.
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Type of Study: Research | Subject: General
Received: 2013/06/16 | Accepted: 2014/07/26 | Published: 2014/07/26

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