Introduction: Owing to the wide variety of jobs and professions in hospitals, many risk factors threaten staff health. The current study examines the relationship between staff’s job accidents and the resulting absence in hospitals of Tehran and Iran universities of Medical Sciences.

Methods: This was a cross-sectional study. Data were collected by questionnaires asking different staff about their job accidents through 2013 in 26 hospitals of Tehran and Iran Universities of Medical Sciences. The Chi-square and independent t tests were used to examine the relationship between job accidents and absence.

Results: 368 completed questionnaires were returned out of 385 distributed ones. Body cut resulted from pointed and sharp objects with 77.2 percent and burns with 6.7 percent were the most and least prevalent accidents among staff respectively. Skin touch with patients’ blood and other fluids was reported as the most absence-causing factor with 92 days, and on the other hand staff accident with trolleys and beds, burns and electricity shock resulted in no day of absence. A meaningful relationship was found between the type of accidents and the resulted days of absence.

Conclusion: Blood and other biological fluids were the main risk factors for staff to send them off their job. For improving staff efficiency and effectiveness, the job accidents should be investigated based on their resulted absence days and corrective considerations are respected.