Volume 4, Issue 1 And 2 (Occupational Medicine Quarterly Journal 2012)                   tkj 2012, 4(1 And 2): 9-16 | Back to browse issues page

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Barkhordri A, Raee Bandpey T, Hekmati Moghaddam S, Mosadegh M, Fallahzadeh H. Evaluation of cholinesterase level in workers exposed to organophosphates . tkj 2012; 4 (1 and 2) :9-16
URL: http://tkj.ssu.ac.ir/article-1-164-en.html
Evaluation of cholinesterase level in workers exposed to organophosphates
A Barkhordri , T Raee Bandpey * , SH Hekmati Moghaddam , MH Mosadegh , H Fallahzadeh
Department of Occupational Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , : raee.tahereh@yahoo.com
Abstract:   (7370 Views)
Background: Organophosphates use in agriculture and concern about their effects on human is increasing. This study was conducted to investigate the activity of blood cholinesterase in sprayers. Methods: In a descriptive and analytical cross-sectional study, 60 (30 sprayers and 30 control individuals) with age range of 29-62 years, mean age of 44.33±8.55 years were studied and the results were analyzed using SPSS version 11. Results: The average and standard deviation of erythrocyte cholinesterase (AchE) and plasma cholinesterase (PchE) concentration was 5573.2± 1229.51 U/L and 144.73±52.3 IU/grHgb, respectively. Minimum and Maximum activity of erythrocyte cholinesterase was also 71.07 and 291.9 IU /gr, respectively. The average concentration of both erythrocyte cholinesterase (AchE) and plasma cholinesterase (PchE) in the case group was lower than the control group. A significant difference was observed between two groups (p<0.05). Conclusion: In conclusion, high exposure to organophosphates was observed and it is needed to implement the occupational health program for prevention of health effects.
Keywords: cholinesterase, biological monitoring, phosphorus pesticides, sprayer.
Full-Text [PDF 188 kb]   (4829 Downloads)    
Type of Study: Research | Subject: Chemical agents
Received: 2012/10/12 | Accepted: 2020/04/14 | Published: 2020/04/14
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