Occupational Medicine Quarterly Journal
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tkj
Medical Sciences
http://tkj.ssu.ac.ir
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2251-7189
2251-8274
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fa
jalali
1399
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gregorian
2020
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ارتباط سطح سرمی روی با وزوز گوش در بیماران با کاهش شنوایی
Investigation of Serum Zinc Level in Patients with Hearing Loss and its Association with Tinnitus
عمومى
General
كاربردي
Applicable
<strong><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">مقدمه</span></span></strong><strong><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">:</span></span></strong> <span style="font-family:B Nazanin;">در</span> <span style="font-family:B Nazanin;">این</span> <span style="font-family:B Nazanin;">مطالعه</span> <span style="font-family:B Nazanin;">در</span> <span style="font-family:B Nazanin;">صدد</span> <span style="font-family:B Nazanin;">شدیم</span> <span style="font-family:B Nazanin;">تا</span> <span style="font-family:B Nazanin;">به</span> <span style="font-family:B Nazanin;">بررسی</span> <span style="font-family:B Nazanin;">سطح</span> <span style="font-family:B Nazanin;">سرمی</span> <span style="font-family:B Nazanin;">روی</span> <span style="font-family:B Nazanin;">در</span> <span style="font-family:B Nazanin;">بیماران</span> <span style="font-family:B Nazanin;">مبتلا</span> <span style="font-family:B Nazanin;">کاهش</span> <span style="font-family:B Nazanin;">شنوایی</span> <span style="font-family:B Nazanin;">بپردازیم</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">ارتباط</span> <span style="font-family:B Nazanin;">آن</span> <span style="font-family:B Nazanin;">را</span> <span style="font-family:B Nazanin;">با</span> <span style="font-family:B Nazanin;">میزان</span> <span style="font-family:B Nazanin;">وزوز</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">بیماران</span> <span style="font-family:B Nazanin;">بسنجیم</span><span style="font-family:B Nazanin;">.</span><br>
<strong><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">روش بررسی</span></span></strong><strong><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">:</span></span></strong> <span style="font-family:B Nazanin;">در</span> <span style="font-family:B Nazanin;">این</span> <span style="font-family:B Nazanin;">مطالعه</span> <span style="font-family:B Nazanin;">مقطعی</span><span style="font-family:B Nazanin;"> 110 </span><span style="font-family:B Nazanin;">نفر</span> <span style="font-family:B Nazanin;">از</span> <span style="font-family:B Nazanin;">بیماران</span> <span style="font-family:B Nazanin;">بالای</span><span style="font-family:B Nazanin;"> 20 </span><span style="font-family:B Nazanin;">سال</span> <span style="font-family:B Nazanin;">که</span> <span style="font-family:B Nazanin;">با</span> <span style="font-family:B Nazanin;">شکایت</span> <span style="font-family:B Nazanin;">کاهش</span> <span style="font-family:B Nazanin;">شنوایی</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">وزوز گوش</span> <span style="font-family:B Nazanin;">به</span> <span style="font-family:B Nazanin;">درمانگاه</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">حلق</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">بینی</span> <span style="font-family:B Nazanin;">مراجعه</span> <span style="font-family:B Nazanin;">کردند،</span> <span style="font-family:B Nazanin;">مورد</span> <span style="font-family:B Nazanin;">بررسی</span> <span style="font-family:B Nazanin;">قرار</span> <span style="font-family:B Nazanin;">گرفتند</span><span style="font-family:B Nazanin;">. </span><span style="font-family:B Nazanin;">بیماران</span> <span style="font-family:B Nazanin;">شرکتکننده</span> <span style="font-family:B Nazanin;">در</span> <span style="font-family:B Nazanin;">ابتدا</span> <span style="font-family:B Nazanin;">بهوسیله</span> <span style="font-family:B Nazanin;">یک</span> <span style="font-family:B Nazanin;">متخصص</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">حلق</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">بینی</span> <span style="font-family:B Nazanin;">بهوسیله</span> <span style="font-family:B Nazanin;">شرححال</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">معاینه</span> <span style="font-family:B Nazanin;">فیزیکی</span> <span style="font-family:B Nazanin;">ویزیت</span> <span style="font-family:B Nazanin;">شده</span> <span style="font-family:B Nazanin;">و ازنظر</span> <span style="font-family:B Nazanin;">کاهش</span> <span style="font-family:B Nazanin;">شنوایی</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">همچنین</span> <span style="font-family:B Nazanin;">اندازهگیری</span> <span style="font-family:B Nazanin;">شدت</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">فرکانس</span> <span style="font-family:B Nazanin;">وزوز</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">توسط</span> <span style="font-family:B Nazanin;">تستهای</span> <span style="font-family:B Nazanin;">شنواییسنجی</span> <span style="font-family:B Nazanin;">استاندارد</span> <span style="font-family:B Nazanin;">تحت</span> <span style="font-family:B Nazanin;">بررسی</span> <span style="font-family:B Nazanin;">قرار</span> <span style="font-family:B Nazanin;">گرفتند</span> <span style="font-family:B Nazanin;">سپس</span> <span style="font-family:B Nazanin;">جهت</span> <span style="font-family:B Nazanin;">بررسی</span> <span style="font-family:B Nazanin;">سطح</span> <span style="font-family:B Nazanin;">سرمی</span> <span style="font-family:B Nazanin;">روی</span> <span style="font-family:B Nazanin;">تحت</span> <span style="font-family:B Nazanin;">نمونهگیری</span> <span style="font-family:B Nazanin;">از</span> <span style="font-family:B Nazanin;">خون</span> <span style="font-family:B Nazanin;">ناشتا</span> <span style="font-family:B Nazanin;">قرار</span> <span style="font-family:B Nazanin;">گرفتند</span><span style="font-family:B Nazanin;">. </span><br>
<strong><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">نتایج</span></span></strong><strong><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">:</span></span></strong> <span style="font-family:B Nazanin;">میانگین</span> <span style="font-family:B Nazanin;">سطح</span> <span style="font-family:B Nazanin;">سرمی</span> <span style="font-family:B Nazanin;">روی</span><span style="font-family:B Nazanin;"> 62/27</span>±<span style="font-family:B Nazanin;">32/85 </span><span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">میانگین</span> <span style="font-family:B Nazanin;">فرکانس</span> <span style="font-family:B Nazanin;">وزوز</span> <span style="font-family:B Nazanin;">گوش</span><span style="font-family:B Nazanin;"> 76/2 </span>±<span style="font-family:B Nazanin;"> 94/4 </span><span style="font-family:B Nazanin;">بوده</span> <span style="font-family:B Nazanin;">که</span> <span style="font-family:B Nazanin;">هر</span> <span style="font-family:B Nazanin;">دو</span> <span style="font-family:B Nazanin;">بین</span> <span style="font-family:B Nazanin;">گروههای</span> <span style="font-family:B Nazanin;">مختلف</span> <span style="font-family:B Nazanin;">اختلاف</span> <span style="font-family:B Nazanin;">معناداری</span> <span style="font-family:B Nazanin;">داشتهاند</span> <span style="font-family:B Nazanin;">(001/0 </span><span dir="LTR">P =</span><span style="font-family:B Nazanin;">). </span><span style="font-family:B Nazanin;">میانگین</span> <span style="font-family:B Nazanin;">شدت</span> <span style="font-family:B Nazanin;">وزوز</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">نیز</span><span style="font-family:B Nazanin;"> 56/4 </span>±<span style="font-family:B Nazanin;"> 77/7 </span><span style="font-family:B Nazanin;">بوده</span> <span style="font-family:B Nazanin;">است</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">بین</span> <span style="font-family:B Nazanin;">گروههای</span> <span style="font-family:B Nazanin;">مختلف</span> <span style="font-family:B Nazanin;">اختلاف</span> <span style="font-family:B Nazanin;">معناداری</span> <span style="font-family:B Nazanin;">نداشته</span> <span style="font-family:B Nazanin;">است</span> <span style="font-family:B Nazanin;">(677/0 </span><span dir="LTR">P =</span><span style="font-family:B Nazanin;">). </span> <span style="font-family:B Nazanin;">سطح</span> <span style="font-family:B Nazanin;">سرمی</span> <span style="font-family:B Nazanin;">روی</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">فرکانس</span> <span style="font-family:B Nazanin;">وزوز</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">با</span> <span style="font-family:B Nazanin;">ضریب</span> <span style="font-family:B Nazanin;">همبستگی</span><span style="font-family:B Nazanin;"> 205/0 </span><span style="font-family:B Nazanin;">(032/0 </span><span dir="LTR">P =</span><span style="font-family:B Nazanin;">) </span><span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">سطح</span> <span style="font-family:B Nazanin;">سرمی</span> <span style="font-family:B Nazanin;">روی</span> <span style="font-family:B Nazanin;">و</span> <span style="font-family:B Nazanin;">میزان</span> <span style="font-family:B Nazanin;">شدت</span> <span style="font-family:B Nazanin;">وزوز</span> <span style="font-family:B Nazanin;">گوش</span> <span style="font-family:B Nazanin;">با</span> <span style="font-family:B Nazanin;">ضریب</span> <span style="font-family:B Nazanin;">همبستگی</span><span style="font-family:B Nazanin;"> 249/0 </span><span style="font-family:B Nazanin;">باهم</span> <span style="font-family:B Nazanin;">در</span> <span style="font-family:B Nazanin;">ارتباط</span> <span style="font-family:B Nazanin;">بودهاند</span> <span style="font-family:B Nazanin;">(009/0 </span><span dir="LTR">P =</span><span style="font-family:B Nazanin;">). </span><span style="font-family:B Nazanin;"></span><br>
<strong><span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">نتیجهگیری</span></span></span></strong><span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:10.0pt;">:</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">با</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">توجه</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">به</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">نتایج</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">مطالعه</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">حاضر</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">تأثیر</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">مثبت</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">سطح</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">سرمی</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">روی</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">بر</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">میزان</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">شدت</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">و</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">فرکانس</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">وزوز</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">گوش</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">مشخص</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">شده</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">است</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">بهگونهای</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">که</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">با</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">کاهش</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">سطح</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">سرمی</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">روی</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">این</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">مقادیر</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">در</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">فرکانسهای</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">پایینتر</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">بروز</span></span></span> <span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">مییابند</span></span></span><span dir="RTL"><span style="font-family:B Nazanin;"><span style="font-size:12.0pt;">.</span></span></span>
<em><strong>Introduction</strong></em>: This study aims to determine the serum zinc level in patients with hearing loss and its relation with tinnitus. <br>
<em><strong>Materials & Methods</strong></em>: In this Cross-Sectional study, 110 patients older than 20 years old with Complaining of hearing loss and tinnitus were involved. Participating patients were first visited by an ear, nose, and throat specialist with a history and physical examination, and were assessed for standard hearing loss as well as the intensity and frequency of tinnitus by standard audiometric tests. Then, fasting blood samples were taken to check serum zinc levels.<br>
Results:The mean serum level was 85.32 ± 27 27.62, and the mean frequency of tinnitus was 4.94 ± 2.76, both of which had significant differences between different groups (P = 0.001). The mean intensity of tinnitus was 7.77 ± 4.56, and there was no significant difference between different groups (P = 0.677). Serum zinc level and tinnitus frequency were associated with a correlation coefficient of 0.205 (P = 0.032), and serum zinc level and tinnitus severity were associated with a correlation coefficient of 0.249 (P = 0.009).<br>
<em><strong>Conclusion</strong></em>: According to the present study results, the positive effect of serum zinc levels on the severity and frequency of tinnitus has been determined so that with decreasing serum zinc levels, tinnitus occurs at lower frequencies.
روی, کاهش شنوایی, وزوز گوش
Serum zinc, Hearing loss, Tinnitus
70
76
http://tkj.ssu.ac.ir/browse.php?a_code=A-10-964-1&slc_lang=fa&sid=1
Vahid
Zand
وحید
زند