fa تاثیر دوازده هفته تمرین عملکردی با شدت بالا و مصرف جینکوبیلوبا بر سطوح سرمی برخی سیتوکین‌های التهابی در آتشنشانان مرد عملیاتی شهر یزد بهداشت حرفه ای Health Professional پژوهشي Research <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span b="" lang="FA" nazanin="" style="font-family:">مقدمه</span></b><b><span b="" lang="AR-SA" nazanin="" style="font-family:">: </span></b><span b="" lang="AR-SA" nazanin="" style="font-family:">تمرینات عملکردی و مصرف گیاه دارویی جینکوبیلوبا، منبع طبیعی فلاونوئیدها و ترکیبات پلی فنلی، اثرات سودمندی در بهبود وضعیت التهابی و عملکرد جسمانی افراد در معرض استرس شغلی دارند. لذا هدف پژوهش حاضر بررسی تاثیر 12 هفته تمرین عملکردی با شدت بالا و مصرف </span><span b="" lang="FA" nazanin="" style="font-family:">عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا بر سطوح سرمی اینترلوکین-8 و اینترلوکین-1</span><span lang="AR-SA" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">&beta;</span></span><span b="" lang="AR-SA" nazanin="" style="font-family:"> در آتشنشانان مرد عملیاتی شهر یزد بود</span><span b="" lang="FA" nazanin="" style="font-family:">. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">روش بررسی: </span></b><span b="" lang="AR-SA" nazanin="" style="font-family:">بدین منظور </span><span b="" lang="FA" nazanin="" style="font-family:">۴۸</span> <span b="" lang="AR-SA" nazanin="" style="font-family:">آتشنشانان مرد به </span><span b="" lang="AR-SA" nazanin="" style="font-family:">طور تصادفی در چهار گروه شامل </span><span b="" lang="AR-SA" nazanin="" style="font-family:">تمرین عملکردی با شدت بالا (</span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">HIFT</span></span><span b="" lang="AR-SA" nazanin="" style="font-family:">)</span><span b="" lang="AR-SA" nazanin="" style="font-family:">، </span><span b="" lang="AR-SA" nazanin="" style="font-family:">تمرین عملکردی با شدت بالا همراه </span><span b="" lang="AR-SA" nazanin="" style="font-family:">با مصرف </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا</span><span b="" lang="AR-SA" nazanin="" style="font-family:">، مصرف </span><span b="" lang="FA" nazanin="" style="font-family:">عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا</span><span b="" lang="AR-SA" nazanin="" style="font-family:"> و کنترل-دارونما قرار گرفتند. </span><span b="" lang="AR-SA" nazanin="" style="font-family:">تمرین </span><span b="" lang="AR-SA" nazanin="" style="font-family:">به مدت 12 هفته و هفته</span><span b="" lang="AR-SA" nazanin="" style="font-family:">‌</span><span b="" lang="AR-SA" nazanin="" style="font-family:">ای 4 جلسه اجرا شد. عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا (80 میلی گرم)</span><span b="" lang="AR-SA" nazanin="" style="font-family:"> به صورت دو کپسول و یک بار در روز بعد از صبحانه به مدت 12 هفته تجویز شد. نمونه</span><span b="" lang="AR-SA" nazanin="" style="font-family:">‌</span><span b="" lang="AR-SA" nazanin="" style="font-family:">های خونی قبل و 48 ساعت پس از آخرین جلسه تمرین گرفته شدند. داده</span><span b="" lang="AR-SA" nazanin="" style="font-family:">‌</span><span b="" lang="AR-SA" nazanin="" style="font-family:">ها با استفاده از تحلیل واریانس دوراهه با نرم افزار 26</span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">SPSS</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">-</span><span b="" nazanin="" style="font-family:"> تجزیه و تحلیل شدند.</span><span lang="AR-SA" style="font-family:"B Nazanin""></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">نتایج: </span></b><span b="" lang="FA" nazanin="" style="font-family:">نتایج نشان</span><span b="" lang="AR-SA" nazanin="" style="font-family:"> داد که اثر متقابل</span><b> </b><span b="" lang="FA" nazanin="" style="font-family:">تمرین و عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا</span> <span b="" lang="FA" nazanin="" style="font-family:">و همچنین اثر تمرین و عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا</span><span b="" lang="AR-SA" nazanin="" style="font-family:"> هر کدام </span><span b="" lang="FA" nazanin="" style="font-family:">به تنهایی باعث کاهش معنی‌دار سطوح سرمی </span><span b="" lang="AR-SA" nazanin="" style="font-family:">اینترلوکین-8 و اینترلوکین-1</span><span lang="AR-SA" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">&beta;</span></span> <span b="" lang="FA" nazanin="" style="font-family:">شد(05/0></span><span dir="LTR" new="" roman="" style="font-family:" times="">p</span><span b="" lang="FA" nazanin="" style="font-family:">). بیشترین درصد تغییرات ایجاد شده در </span><span b="" lang="AR-SA" nazanin="" style="font-family:">اینترلوکین-8 و اینترلوکین-1</span><span lang="AR-SA" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">&beta;</span></span> <span b="" lang="FA" nazanin="" style="font-family:">به دنبال مداخله تمرین همراه با مصرف عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا</span> <span b="" lang="FA" nazanin="" style="font-family:">حاصل شد.</span><b><span lang="AR-SA" style="font-family:"B Nazanin""></span></b></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">نتیجه‌گیری:</span></b><span b="" lang="AR-SA" nazanin="" style="font-family:"> انجام </span><span b="" lang="AR-SA" nazanin="" style="font-family:">تمرینات عملکردی با شدت بالا همراه </span><span b="" lang="AR-SA" nazanin="" style="font-family:">با مصرف </span><span b="" lang="FA" nazanin="" style="font-family:">عصاره </span><span b="" lang="AR-SA" nazanin="" style="font-family:">جینکوبیلوبا</span><span b="" lang="AR-SA" nazanin="" style="font-family:">، بیشترین تأثیر را در </span><span b="" lang="FA" nazanin="" style="font-family:">کاهش سطوح سرمی شاخص&shy;های التهابی </span><span b="" lang="AR-SA" nazanin="" style="font-family:">و بهبود شرایط استرس اکسیداتیو در آتشنشانان داشت.</span></span></span></span></span></span></span><br> <br> <span style="font-size:11pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><span dir="LTR" style="font-size:12.0pt"><span style="line-height:107%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span></span> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Introduction:</span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> functional exercises and consumption of the medicinal plant Ginkgo biloba, a natural source of flavonoids and polyphenolic compounds, have beneficial effects in improving the inflammatory state and physical performance of people exposed to occupational stress. Therefore, the aim of the present study was to investigate the effect of 12 weeks of high-intensity functional training and consumption of Ginkgo biloba extract on the serum levels of interleukin-8 and interleukin-1&beta; in operational male firefighters of Yazd city.</span></span><span dir="RTL" lang="AR-SA" style="font-size:10.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Materials and Methods: </span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">For this purpose, 48 male firefighters were randomly divided into four groups including high-intensity functional training (HIFT), high-intensity functional training with ginkgo biloba consumption, ginkgo biloba extract consumption, and control-placebo. The training was carried out for 12 weeks and 4 sessions per week. Ginkgo biloba extract (80 mg) was administered as two capsules once a day after breakfast for 12 weeks. Blood samples were taken before and 48 hours after the last training session. Data were analyzed using two-way analysis of variance with SPSS-26 software.</span></span><b><span dir="RTL" lang="AR-SA" style="font-size:10.0pt"><span style="font-family:"B Nazanin""></span></span></b></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Results</span></span></b><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">:</span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> The results showed that the interaction effect of exercise and ginkgo biloba extract, as well as the effect of exercise and ginkgo biloba extract alone, caused a significant decrease in the serum levels of interleukin-8 and interleukin-1&beta; (p<0.05). The highest percentage of changes in interleukin-8 and interleukin-1&beta; were obtained following exercise intervention along with the consumption of Ginkgo biloba extract.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> Performing high-intensity functional exercises with Ginkgo biloba extract had the greatest effect in reducing serum levels of inflammatory indicators and improving oxidative stress conditions in firefighters.</span></span><span dir="RTL" lang="AR-SA" style="font-size:10.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span><br> <br> <span style="font-size:11pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><span dir="LTR" style="font-family:"Times New Roman","serif""></span></span></span></span></span></span> تمرین عملکردی, جینکوبیلوبا, سیتوکین, آتشنشانان عملیاتی Functional training, Ginkgo biloba, Cytokine, Operational firefighters. 54 67 http://tkj.ssu.ac.ir/browse.php?a_code=A-11-1320-1&slc_lang=fa&sid=1 Hamid Sedaghat حمید صداقت hsedaghat9194@gmail.com 0009-0001-9785-0081 No PhD Student, Department of Sports Physiology, School of Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran گروه فیزیولوژی ورزش، دانشکده‌ی علوم ورزشی، دانشگاه آزاد اسلامی، واحد اصفهان (خوراسگان)، اصفهان، ایران. Farzaneh Taghian فرزانه تقیان Ft.taghian@gmail.com 0000-0001-9531-2952 Yes Department of Sports Physiology, School of Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran گروه فیزیولوژی ورزشی، دانشکده ی علوم ورزشی، دانشگاه آزاد اسلامی ، واحد اصفهان (خوراسگان)، اصفهان، ایران Khosro Jalali Dehkordi خسرو جلا دهکردی khsrojalali@khuisf.ac.ir 0000-0003-0210-5984 No Department of Sports Physiology, School of Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran گروه فیزیولوژی ورزشی، دانشکده ی علوم ورزشی، دانشگاه آزاد اسلامی ، واحد اصفهان (خوراسگان)، اصفهان، ایران hasan naghizadeh حسن نقی زاده naghizadeh2011@ardakan.ac.ir 0000-0001-8185-7767 No Assistant Professor of Sport Physiology, Ardakan University, Ardakan, Iran. استادیار گروه فیزیولوژی ورزش، دانشگاه اردکان، اردکان، ایران.