Volume 16, Issue 4 (Occupational Medicine Quarterly Journal 2024)
tkj 2024, 16(4): 78-89 |
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Nejatifar F, Attarchi M, Sohrabi M M, Seyedmehdi S M. Management of thrombocytopenia detected in occupational health examinations: A review article. tkj 2024; 16 (4) :78-89
URL: http://tkj.ssu.ac.ir/article-1-1291-en.html
URL: http://tkj.ssu.ac.ir/article-1-1291-en.html
, mohammadseyedmehdi@gmail.com
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Management of thrombocytopenia detected in occupational health examinations: A review article
Nejatifar F 1, Attarchi MS 2, Sohrabi M 3, Seyedmehdi SM 4[**]
1 Associate Professor of Hematology & Oncology, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
2 Professor of Occupational Medicine, Department of Forensic Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
3 Occupational Medicine specialist in ASA, Occupational Medicine Center
4 Associate Professor of Occupational Medicine ,Department of Pathology, School of Medicine Chronic Respiratory Diseases Research Center Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
Introduction: The accidental discovery of thrombocytopenia is a medical challenge and may be of little clinical importance or indicate a serious disease affecting the hematopoietic system. In this article, we have discussed how to manage incidental isolated thrombocytopenia identified during occupational health examinations.
Materials and Methods: In this study, to effectively address the thrombocytopenia found accidentally in screening tests, researchers searched reliable databases such as Scopus, PubMed, Google Scholar, and others.
Results: In general, thrombocytopenia may result from a decrease in platelet production, an increase in platelet consumption, or an increase in platelet separation from the circulatory system. In dealing with thrombocytopenia, a thorough history, physical examination, and targeted laboratory tests can identify patients who need immediate intervention. Common causes of thrombocytopenia include false thrombocytopenia, drug use, congenital thrombocytopenia, chronic liver disease, distributed thrombocytopenia, concurrent deficiency of folic acid and vitamin B12, immune thrombocytopenia purpura, thrombotic thrombocytopenic purpura, viral infections, and systemic autoimmune disorders. Additionally, assessing the risk of bleeding in these individuals should be considered.
Conclusion: Thrombocytopenia discovered in screening tests is a relatively common finding and has numerous underlying causes. A systematic approach is required to identify its underlying causes. Knowing the list of common benign causes of isolated thrombocytopenia and the alarm symptoms of this disorder can help an occupational health specialist identify high-risk people and take the necessary measures.
Keywords: Thrombocytopenia, Screening test, Occupational qualification, Bleeding, Blood platelets
*Corresponding Author:
Email: mohammadseyedmehdi@gmail.com
Tel: +98 -2127123250
Received: 04.04.2024 Accepted: 24.11.2024
Full-Text: (25 Views)
Management of thrombocytopenia detected in occupational health examinations: A review article
Nejatifar F 1, Attarchi MS 2, Sohrabi M 3, Seyedmehdi SM 4[**]
1 Associate Professor of Hematology & Oncology, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
2 Professor of Occupational Medicine, Department of Forensic Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
3 Occupational Medicine specialist in ASA, Occupational Medicine Center
4 Associate Professor of Occupational Medicine ,Department of Pathology, School of Medicine Chronic Respiratory Diseases Research Center Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
Introduction: The accidental discovery of thrombocytopenia is a medical challenge and may be of little clinical importance or indicate a serious disease affecting the hematopoietic system. In this article, we have discussed how to manage incidental isolated thrombocytopenia identified during occupational health examinations.
Materials and Methods: In this study, to effectively address the thrombocytopenia found accidentally in screening tests, researchers searched reliable databases such as Scopus, PubMed, Google Scholar, and others.
Results: In general, thrombocytopenia may result from a decrease in platelet production, an increase in platelet consumption, or an increase in platelet separation from the circulatory system. In dealing with thrombocytopenia, a thorough history, physical examination, and targeted laboratory tests can identify patients who need immediate intervention. Common causes of thrombocytopenia include false thrombocytopenia, drug use, congenital thrombocytopenia, chronic liver disease, distributed thrombocytopenia, concurrent deficiency of folic acid and vitamin B12, immune thrombocytopenia purpura, thrombotic thrombocytopenic purpura, viral infections, and systemic autoimmune disorders. Additionally, assessing the risk of bleeding in these individuals should be considered.
Conclusion: Thrombocytopenia discovered in screening tests is a relatively common finding and has numerous underlying causes. A systematic approach is required to identify its underlying causes. Knowing the list of common benign causes of isolated thrombocytopenia and the alarm symptoms of this disorder can help an occupational health specialist identify high-risk people and take the necessary measures.
Keywords: Thrombocytopenia, Screening test, Occupational qualification, Bleeding, Blood platelets
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This paper should be cited as:
Nejatifar F, Attarchi MS, Sohrabi M, Seyedmehdi SM. Management of thrombocytopenia detected in occupational health examinations: A review article. Occupational Medicine Quarterly Journal. 2025:16(4): 78-89. |
Email: mohammadseyedmehdi@gmail.com
Tel: +98 -2127123250
Received: 04.04.2024 Accepted: 24.11.2024
Type of Study: Review Article |
Subject:
occupational medicine
Received: 2024/04/4 | Accepted: 2024/11/24 | Published: 2024/12/30
Received: 2024/04/4 | Accepted: 2024/11/24 | Published: 2024/12/30
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